Jardiance is a daily oral medication used to manage blood sugar levels for people who suffer from type 2 diabetes.
This is achieved by aiding the kidneys in removing glucose from the bloodstream via the urine.
The Jardiance assistance program does not aid in weight reduction or blood pressure management However, it can assist in both. It can be used as part of a plan of treatment which may include exercise, diet, and medical treatment.
It was approved by European Commission in May 2014. Since it is a relatively new medication and a relatively new drug, its long-term effects over several years are not established.
About Jardiance
The trade name is Jardiance
Genric Name: Empagliflozin
Class of drug: SGLT2 inhibitors
Manufacturer Boehringer Ingelheim and Lilly Diabetes
What does Jardiance aid with type 2 diabetes?
By eliminating excess sugar from your body via the urine, Jardiance assists in enhance glycemic control for people suffering from Type 2 Diabetes. This may result in better HbA1c level, which may lower the risk of developing complications related to diabetes.
Because glucose’s calories are eliminated by the body. This means that weight reduction could be a result of Jardiance. Because type 2 diabetes is highly linked to weight – around 90% of those newly diagnosed with type 2 diabetes have a weight that is above the ideal which is beneficial to keeping the weight of a healthy person.
Jardiance is used as a part of a treatment plan and it is crucial to continue other aspects including physical fitness in addition to Jardiance treatment.
Mechanism of action
Empagliflozin can be described as an SGLT2 inhibitor, a class of drugs that assists in stopping sodium-glucose transport proteins that have been removed from kidneys’ bloodstream getting absorbed back into blood.
Empagliflozin permits a substantial quantity of glucose to be eliminated by urine. It is believed that the SGLT2 protein is responsible for 90%% of the glucose returned to the blood.
Who do you think Jardiance appropriate for?
Jardiance is suggested by National Institute of Clinical Excellence (NICE) as an option for treating type 2 diabetes in those conditions
When exercise and diet don’t provide enough glucose control
If metformin isn’t appropriate due to intolerance of the patient
Jardiance may be prescribed in addition to metformin when patients are at high danger of having hypoglycemia or is unable to use an Sulfonylurea. It is also possible to take alongside metformin or a Sulfonylurea.
Who should not be able to resist Jardiance?
It is not recommended to be taking Jardiance in the event that you are:
Type 1 diabetes
Severe kidney problems
Before you take Jardiance it is recommended to discuss with your doctor if:
Are you suffering from kidney issues?
Are you pregnant or plan to be expecting or planning to become
Are you nursing, or plan to breastfeed?
Have you had liver issues?
Have a low blood pressure
Use blood pressure medications
Are you suffering from high cholesterol levels?
Are you a victim or a history of infections in the urinary tract
Are you 65 or more
Are you on a diet that is low in salt?
What should Jardiance be handled?
Jardiance is taken orally and typically taken daily in the morning. It can be taken without or with food.
The medication is initially prescribed in a dose of 10 mg but the maximum dose is 25 mg. Your doctor can alter the dose of your medication to ensure you are getting the most benefit However, you shouldn’t use Jardiance in lower or higher doses than what is recommended.
If you are unable to take an dose, it is recommended to start taking it whenever you remember. But, do not have an extra dose in order to compensate for missing medication. If it’s almost time to take your next dose, then you can not take the dose you missed previously.
Storage
Jardiance is best stored at room temperature, away from heat and moisture. It should be kept in the original container. It must be ensured that it’s out of sight and reach of young children.
What are the negative effects of Jardiance?
The adverse consequences of Jardiance are:
Urinary problems – whether it’s an urge to urinate frequently or a lack of being able to urinate.
More likely to contract urinary tract infections
The signs of a genital infection include itching, pain, or the appearance of a skin rash
Hypoglycemia is a condition that can be treated along with a medication which reduces blood glucose levels
The increase in cholesterol
Feeling lightheaded or tired
It is important to note that the list above isn’t complete. It is recommended to look up the leaflet for patients that comes with the medication to get a complete list of adverse consequences.
What should you do if have taken an overdose
If you have taken an overdose of Jardiance make contact with your health care provider immediately to seek advice.
Long-term safety
There are concerns about whether SGLT2 inhibitors can have a negative long-term impact on the kidneys. Invokana is in the same class as Jardiance and has been associated with a decline in eGFR which is a measure that measures kidney function.
Based on the European Medicines Agency, the most commonly reported adverse reaction with Jardiance was hypoglycemia. This resulted when the drug was combined in conjunction with insulin or sulphonylurea.
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